RE: Skull extracted denoised output

[color=#000000]Hi Panos,[/color]

[color=#000000]Yes, you are right, that sounds like a product of the percent signal change (PSC) scaling of the BOLD signal, since the estimated global BOLD signal will be considerably smaller when using the 'none' masking option compared to explicit- or implicit- masking (in this case I would probably recommend skipping PSC-scaling entirely).[/color]

[color=#000000]Best[/color]
[color=#000000]Alfonso[/color]

[i]Originally posted by Panos Fotiadis:[/i][quote]Hi Alfonso,

Thank you, that is extremely helpful!
I just ran the "no masking" option for right now and noticed that the value at each voxel between the non-masked denoised volume is approximately 3x the value of the equivalent voxel in the masked denoised volume. Is that because each value (at each voxel) represents the percent BOLD signal difference between the raw BOLD value of that voxel and the mean BOLD value of the whole brain (and the mean BOLD signal is now different in each case)? 

Thanks again,
Panos[/quote]