Dear brain reseachers
Please let me know about the 2nd level analysis.
I have two groups, patients and the controls.
I have done between group comparison by ROI-to-ROI analysis including age as a nuisance covariate.
This yielded multiple supra-threshold connections.
I have neuropsychological tests results in the patients. I want to know which connections are significantly associated with the test- score.
When I want to restrict analysis within the connections that showed significant changes in the group comparison, how contrast should look like? Test -scores of controls are lacking, so I put 0 in test-score of the controls.
Covariate was defined as follows;
patient controls age test-score
Is contrast [ 1 -1 0 1] correct to identify connections particularly associated with the test score?
I would appreciate answer to this question.
Regards,
Ken Kazumata, Japan.
Please let me know about the 2nd level analysis.
I have two groups, patients and the controls.
I have done between group comparison by ROI-to-ROI analysis including age as a nuisance covariate.
This yielded multiple supra-threshold connections.
I have neuropsychological tests results in the patients. I want to know which connections are significantly associated with the test- score.
When I want to restrict analysis within the connections that showed significant changes in the group comparison, how contrast should look like? Test -scores of controls are lacking, so I put 0 in test-score of the controls.
Covariate was defined as follows;
patient controls age test-score
Is contrast [ 1 -1 0 1] correct to identify connections particularly associated with the test score?
I would appreciate answer to this question.
Regards,
Ken Kazumata, Japan.