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between subject contrasts question

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Hi! I am currently working on an analysis looking at cognitive control networks and their correlation to maternal reading fluency in children. When looking at the between subjects contrast in conn, if I want to look at the effects of TOSREC (maternal reading fluency) scores on All subjects could I use the main effect of both All subjects and TOSREC [0.5 0.5] or does it need to be the simple main effect of TOSREC [0 1]? Thanks!

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