I am doing an analysis looking within a group to see how glutamate concentrations predict intrinsic functional connectivity in a seed region.
I ran across this previous thread for someone with a similar issue to me... http://www.nitrc.org/forum/message.php?msg_id=19775
I have a significant cluster coming out of my analysis which is mostly white matter (near the corpus callosum, I think). I've gone back and checked the registration of structural to functional scans, looked at smoothing results, investigated the histogram of functional connectivity values. Nothing seems obviously wrong. Of course, the white matter and grey matter registrations are not perfect during preprocessing, but that's to be expected, isn't it? It seems weird that I am getting this result at the group level?
I haven't yet gone back and done the analysis with high vs. low movement groups, but I have already removed participants from the study with over 20% of scans showing movement.
What options do I have here? How do I report a result that is mostly white matter when this should be regressed out during the analysis? Any thoughts here? Would it be fair to say that this result is likely a slight misregistration between white matter and grey matter which can occur in this region? Should I even report it?
Help please!
I have attached the result below.
Thanks in advance, I would be lost without this help forums advice!! :)
I ran across this previous thread for someone with a similar issue to me... http://www.nitrc.org/forum/message.php?msg_id=19775
I have a significant cluster coming out of my analysis which is mostly white matter (near the corpus callosum, I think). I've gone back and checked the registration of structural to functional scans, looked at smoothing results, investigated the histogram of functional connectivity values. Nothing seems obviously wrong. Of course, the white matter and grey matter registrations are not perfect during preprocessing, but that's to be expected, isn't it? It seems weird that I am getting this result at the group level?
I haven't yet gone back and done the analysis with high vs. low movement groups, but I have already removed participants from the study with over 20% of scans showing movement.
What options do I have here? How do I report a result that is mostly white matter when this should be regressed out during the analysis? Any thoughts here? Would it be fair to say that this result is likely a slight misregistration between white matter and grey matter which can occur in this region? Should I even report it?
Help please!
I have attached the result below.
Thanks in advance, I would be lost without this help forums advice!! :)