Dear Dr. Alfonso, thank you for your help in the forum. I am wondering what kind of inference can I make if I had no a priori hypothesis and just selected all the ROIS in the brain to a Roi-to-ROi analysis in a study where I am comparing pre and post intervention of a Treatment vs sham. I chose the cluster base inference - Functional network connectivity. I attached the images from my analysis for clarity purposes. I am not sure what can I conclude from this image:
Can I conclude that between each Roi I see, there is a greater connectivity ( in the case of red lines - since the contrast I used was -1 pre 1 post and 1 treatment -1 sham) change in the treatment group? or since it is a cluster inference I can only conclude that there is somewhere in the cluster a greater connectivity but cannot conclude this for each ROi individualy? In other words can I say these areas are more connected after the treatment or am I only aloud to say that somewhere in these areas there is a true greater connectivity?
Thank you for your Help,
Marco Echevarria
Can I conclude that between each Roi I see, there is a greater connectivity ( in the case of red lines - since the contrast I used was -1 pre 1 post and 1 treatment -1 sham) change in the treatment group? or since it is a cluster inference I can only conclude that there is somewhere in the cluster a greater connectivity but cannot conclude this for each ROi individualy? In other words can I say these areas are more connected after the treatment or am I only aloud to say that somewhere in these areas there is a true greater connectivity?
Thank you for your Help,
Marco Echevarria